PhytoSpherix™ can also confer increased phase stability, storage stability, and in mixing procedures where other ingredients are introduced as an additional step.
The impact of PhytoSpherix™ on emulsion stability was evaluated with accelerated stability tests. Oil-in-water emulsions containing 0.5% PhytoSpherix™ or 0.5% hyaluronic acid were centrifuged for 2 min at 8000 rpm and inspected for visible signs of phase separation. The emulsion containing hyaluronic acid showed significant phase separation but the PhytoSpherix™ sample did not (Image 1). Emulsions containing either PhytoSpherix™ or hyaluronic acid were also stored at 45 °C for 2 months and compared. The hyaluronic acid emulsion separated into two distinct phases but the PhytoSpherix™ emulsion did not show any visible signs of instability (Image 2).
Image 1. Rapid Centrifuge Test
Image 2. Accelerated Stability Test (2 months @ 45°C)