Skin Hydration

PhytoSpherix® nanoparticles have exceptional water retention properties.  This property is highly desirable in moisturizing cosmetic preparations, e.g. lotions and creams. The water retention of PhytoSpherix® even outperforms the current gold standard in moisturizers: hyaluronic acid.  IR data shows that PhytoSpherix® has more strongly bound water than hyaluronic acid.

Fig. 1 IR Spectra of PhytoSpherix® and Hyaluronic Acid 

(Adapted from Grossutti, M.; Dutcher, J.R. Biomacromolecules 2016, 17, 1198-1204)


Skin hydration tests using the corneometry technique show that PhytoSpherix® hydrates the skin better than hyaluronic acid, and demonstrates a synergistic effect when used together (see Figure 2).

Fig. 2 Skin Hydration Study
Hydration graph

The skin feel of a cream containing PhytoSpherix® was compared to the same cream containing hyaluronic acid in a blind study.  Participants ranked the PhytoSherix® cream higher than the hyaluronic acid cream in all evaluated qualities, and 100% of participants preferred the PhytoSpherix® cream overall (see Figure 3).

Fig. 3 Sensory Analysis

sensory 2