Glycogen Metabolism in the Skin

UV light irradiation induces an increase in glycogen content in the epidermis. Increased cellular glycogen content is one of the responses of epidermal cells to wounding and the glycogen is believed to provide the energy necessary to meet the demand of rapid growth often attributed to disturbed epidermal cells.

Glycogen is present in embryonic epithelial cells and appear again under conditions of inflammation or abnormal proliferation in epidermis, provoked by exposure to UV light, cuts or abrasions. Glycogen metabolism operates as an alternative energy source, enabling cell growth under conditions of metabolic stress.